Association of Lifelines Diet Score (LLDS) with type 2 diabetes mellites and hypertension: a cross-sectional study
DOI:
https://doi.org/10.15218/hcchs.2023.06Keywords:
Lifelines Diet Score, LLDS, Type 2 Diabetes Mellitus, Hypertension, Cross-Sectional StudyAbstract
Background and objective: Type 2 diabetes mellitus (T2DM) and hypertension are prevalent chronic conditions associated with significant health burdens. Diet plays a critical role in the development and management of both diseases. This cross-sectional study aimed to investigate the association between Lifelines Diet Score (LLDS) and the risk of type 2 diabetes mellitus (T2DM) and hypertension.
Methods: A cross sectional study was conducted according to a single protocol and at a single site, from February 2023 to March and completed a food frequency questionnaire (FFQ) to calculate their LLDS. T2DM and hypertension status were determined through medical records and participant interviews. Statistical analyses were conducted to examine the association between LLDS and the prevalence of T2DM and hypertension, adjusting for potential confounders.
Results: A total of 411 participants were included in the study. Participants in higher LLDS tertiles exhibited significantly lower risks of T2DM and hypertension compared to those in lower tertiles. In the crude model, the second tertile showed a 40% lower risk of T2DM, while the third tertile had a 45% lower risk (P < 0.001). Similar patterns were observed for hypertension, with the second tertile showing a 16% lower risk (P < 0.001) and the third tertile exhibiting a 38% lower risk (P < 0.001). These associations remained significant after adjusting for cofounder factors (age, energy intakes, carbohydrate, protein, fat, physical activity, and BMI).
Conclusions: The findings of this cross-sectional study suggest that adherence to a healthier dietary pattern, as indicated by higher LLDS scores, is associated with a reduced risk of T2DM and hypertension. These results highlight the importance of overall diet quality in the prevention and management of T2DM and hypertension.
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