A Novel Production of Multiple Phyto-Nanoparticles and Their Activity as Anti Head Lice and its Overlapping Bacteria
DOI:
https://doi.org/10.15218/hcchs.2023.04Keywords:
Nanotechnology, Henna, Lawsoniainermis, Spectroscopy, BabylonAbstract
Background and objective: Nanotechnology is defined as a highly developed technology due to its wide range of applications in various fields of medical science, technology, and other research fields. Green synthesis methods are environmentally friendly, readily available, safe and non-toxic. The Objective of the present study is to producing nanoparticles from plant in addition to evaluation the effectiveness of the extracted nanoparticles as anti head lice and it is overlapping bacteria.
Methods: In this study, several nits were collected and more than 44 adult lice were screened for bacteria. Ethanol and Deionized water was used to obtain nanoparticles from Henna leaves, Lawsonia inermis. The characterization process was performed using UV-visible spectroscopy techniques, energy dispersive X-ray spectroscopy (EDX) and atomic factor microscopy (AFM). Pharmaceutical activity of the isolated nanoparticles was determined through using of agar diffusion test and in vitro study of the nit embryonic development.
Results: The results of the study include the identification of several nanoparticles from Henna leaf extract, including cadmium, iron, nickel, zinc, copper, cobalt, manganese, and silver, with different concentration density ranged from 10 nm to 50 nm, with a percentage of 80%. Obtained nanoparticles (especially 15μL in concentration) can penetrate the wall of the nit shell and reach the embryo followed by inhibition of it is growth also play a powerful role in eliminating and inhibiting the lice overlapping bacteria.
Conclusion: Development of a new drug product to treat and control the growth of head lice Phyto-multinanoparticles- is play a strong role in the eradication and inhibition of the nits and lice overlapping bacteria.
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